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CAPON Antibody, Cy3 Conjugated

CAPON Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, CAPON Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCAPON
SpecificityThis is a highly specific antibody against CAPON
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CAPON
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, The association of nNOS with PSD95 or PSD93 is regulated by CAPON, The carboxy terminus of CAPON binds to the PDZ domain, These proteins facilitate the transport of nNOS to the plasma membrane, and sequesters nNOS in the cytosol, but not to endothelial NOS or inducible NOS, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain, where it is catalytically activated by NMDA-receptor mediated calcium channels, CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms KIAA0464 CAPON
Properties 1 of the CAPON Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCAPON Conjugated
Short name Conjugated, CAPON Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, CAPON (Antibody to)
Alternative techniqueantibodies
Identity 16859
Gene NOS1AP
Long gene name nitric oxide synthase 1 adaptor protein
Synonyms gene name nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms name C-terminal PDZ domain ligand of neuronal nitric oxide synthase
Locus 1q23, 3
Discovery year 2005-06-15
GenBank acession AB007933
Entrez gene record 9722
Pubmed identfication 9455484 9459447
RefSeq identity NM_014697
Havana BLAST/BLAT OTTHUMG00000024049

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