Filters

Carboxypeptidase B2 Antibody / CPB2 / TAFI

Carboxypeptidase B2 Antibody / CPB2 / TAFI size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCarboxypeptidase B2 / CPB2 / TAFI
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, Western blot
Recommended dilutions5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis Carboxypeptidase B2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q96IY4
PurityAntigen affinity
Description Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen, CPB2 exhibits carboxypeptidase activity, CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen, When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, also known as carboxypeptidase U (CPU), in humans, is an enzyme that, is encoded by the gene CPB2, plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), Carboxypeptidase B2 (CPB2)
ImmunogenAmino acids K166-D388 from the human protein were used as the immunogen for the Carboxypeptidase B2 antibody
Storage After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, store at 4oC, the Carboxypeptidase B2 antibody may be kept for up to one month refrigerated at +4 degrees C, For long-term, Prior to reconstitution
LocalizationCytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCarboxypeptidase B2 / CPB2 / TAFI
Short nameCarboxypeptidase B2 Antibody / CPB2 / TAFI
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCarboxypeptidase B2 (Antibody to) / CPB2 / TAFI
Alternative techniqueantibodies
Identity 2300
Gene CPB2
Long gene name carboxypeptidase B2
Synonyms gene name carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 (plasma)
Synonyms CPU PCPB TAFI
Synonyms name thrombin-activatable fibrinolysis inhibitor carboxypeptidase U plasma carboxypeptidase B carboxypeptidase R
Locus 13q14, 13
Discovery year 1992-04-10
GenBank acession M75106
Entrez gene record 1361
Pubmed identfication 1939207 1427879
RefSeq identity NM_001872
Classification Carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000016867

Subscribe to our Newsletter