Name : CARD14 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9608834437
| Long name | ALEXA FLUOR 350 Conjugated, CARD14 Polyclonal Antibody |
| Also known as | Anti-CARD14 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CARD14 |
| Specificity | This is a highly specific antibody against CARD14 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD14 |
| Gene ID Number | 79092 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | The CARD domains of both proteins have been shown to specifically interact with BCL10, This protein is also a member of the CARD protein family, This protein shares a similar domain structure with CARD11 protein, Two alternatively spliced variants of this gene encoding distinct isoforms have been reported, When expressed in cells, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation, this protein activated NF-kappaB and induced the phosphorylation of BCL10, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD), The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | CARMA2 BIMP2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | CARD14 |
| Short name | CARD14 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, member 14 (Antibody to), caspase recruitment domain family |
| Alternative technique | antibodies |
| Alternative to gene target | CARD domain binding, CARD14 and IDBG-642674 and ENSBTAG00000015261 and 523360, CARD14 and IDBG-71483 and ENSG00000141527 and 79092, Card14 and IDBG-214692 and ENSMUSG00000013483 and 170720, Plasma membranes, member 14, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0050700: CARD domain binding, this GO :0050700: CARD domain binding, caspase recruitment domain family |
| Identity | 16446 |
| Gene | CARD14 |
| Long gene name | caspase recruitment domain family member 14 |
| Synonyms gene | PSORS2 |
| Synonyms gene name | member 14 , psoriasis susceptibility 2 caspase recruitment domain family |
| Locus | 17q25, 3 |
| Discovery year | 2002-09-19 |
| GenBank acession | AF322642 |
| Entrez gene record | 79092 |
| Pubmed identfication | 11278692 11356195 22521418 |
| Classification | Caspase recruitment domain containing Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000177549 |