Name : CARD14 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7696565045
| Long name | ALEXA FLUOR 647 Conjugated, CARD14 Polyclonal Antibody |
| Also known as | Anti-CARD14 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CARD14 |
| Specificity | This is a highly specific antibody against CARD14 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD14 |
| Gene ID Number | 79092 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | The CARD domains of both proteins have been shown to specifically interact with BCL10, This protein is also a member of the CARD protein family, This protein shares a similar domain structure with CARD11 protein, Two alternatively spliced variants of this gene encoding distinct isoforms have been reported, When expressed in cells, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation, this protein activated NF-kappaB and induced the phosphorylation of BCL10, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD), The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | CARMA2 BIMP2 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CARD14 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | CARD14 |
| Short name | CARD14 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, member 14 (Antibody to), caspase recruitment domain family |
| Alternative technique | antibodies |
| Alternative to gene target | CARD domain binding, CARD14 and IDBG-642674 and ENSBTAG00000015261 and 523360, CARD14 and IDBG-71483 and ENSG00000141527 and 79092, Card14 and IDBG-214692 and ENSMUSG00000013483 and 170720, Plasma membranes, member 14, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0050700: CARD domain binding, this GO :0050700: CARD domain binding, caspase recruitment domain family |
| Identity | 16446 |
| Gene | CARD14 |
| Long gene name | caspase recruitment domain family member 14 |
| Synonyms gene | PSORS2 |
| Synonyms gene name | member 14 , psoriasis susceptibility 2 caspase recruitment domain family |
| Locus | 17q25, 3 |
| Discovery year | 2002-09-19 |
| GenBank acession | AF322642 |
| Entrez gene record | 79092 |
| Pubmed identfication | 11278692 11356195 22521418 |
| Classification | Caspase recruitment domain containing Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000177549 |