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CARD14 Antibody, FITC Conjugated

CARD14 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CARD14 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCARD14
SpecificityThis is a highly specific antibody against CARD14
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CARD14
Gene ID number79092
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background The CARD domains of both proteins have been shown to specifically interact with BCL10, This protein is also a member of the CARD protein family, This protein shares a similar domain structure with CARD11 protein, Two alternatively spliced variants of this gene encoding distinct isoforms have been reported, When expressed in cells, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation, this protein activated NF-kappaB and induced the phosphorylation of BCL10, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD), The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CARMA2 BIMP2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCARD14 Conjugated
Short name FITC Conjugated, CARD14 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, member 14 (Antibody to), caspase recruitment domain family
Alternative techniqueantibodies
Alternative to gene target CARD domain binding, CARD14 and IDBG-642674 and ENSBTAG00000015261 and 523360, CARD14 and IDBG-71483 and ENSG00000141527 and 79092, Card14 and IDBG-214692 and ENSMUSG00000013483 and 170720, Plasma membranes, member 14, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0050700: CARD domain binding, this GO :0050700: CARD domain binding, caspase recruitment domain family
Identity 16446
Gene CARD14
Long gene name caspase recruitment domain family member 14
Synonyms gene PSORS2
Synonyms gene name member 14 , psoriasis susceptibility 2 caspase recruitment domain family
Locus 17q25, 3
Discovery year 2002-09-19
GenBank acession AF322642
Entrez gene record 79092
Pubmed identfication 11278692 11356195 22521418
Classification Caspase recruitment domain containing Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000177549

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