Filters

Casein Kinase II α (8E5) Monoclonal Antibody

Casein Kinase II α (8E5) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name (8E5) Monoclonal Antibody, Casein Kinase II &alpha
Also known as (8E5) Monoclonal Antibody, Casein Kinase II &alpha
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCasein Kinase II &alpha
SpecificityThis is a highly specific antibody against Casein Kinase II &alpha
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number800000
Concentration2ug/ul
SourceRecombinant human protein purified from E, coli(His-Casein kinase II a)
Gene ID number1457
Swiss ProtP68400
Tested Applications IP, WB
Recommended dilutions0ug/mL) IP (2ug), WB (2
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ATF1, Acts as an ectokinase that phosphorylates several extracellular proteins, Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, Also required for p53/TP53-mediated apoptosis, CMV and HPV, CREB1, Can also negatively regulate apoptosis, During mitosis, During viral infection, FOS, HBV, HCV, HIV, HSV, II, III and IV, IRF1, IRF2, JUN, MAX, MYC and MYB, May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response, Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation, Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3, Phosphorylation protects CASP9 from cleavage and activation by CASP8, Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1, Regulates numerous cellular processes, Regulates transcription by direct phosphorylation of RNA polymerases I, SRF, STAT1, and inhibits the dimerization of CASP2 and activation of CASP8, apoptosis and transcription, as well as viral infection, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage, phosphorylates various proteins involved in the viral life cycles of EBV, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation, such as cell cycle progression, which is essential for chaperone function, Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CK II alpha, CK2A1, CSNK2A1, CSNK2A3, Casein kinase II subunit alpha, OCNDS, CKII
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target (8E5) Monoclonal, Casein Kinase II &alpha
Short name (8E5) Monoclonal Antibody, Casein Kinase II &alpha
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name (8E5) monoclonal (Antibody to), Casein phosphorylation catalyst II &alpha
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter