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CASK/CAMGUK Antibody, ALEXA FLUOR 488

CASK/CAMGUK Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, CASK/CAMGUK Polyclonal Antibody
Also known asAnti-CASK/CAMGUK PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCASK/CAMGUK
SpecificityThis is a highly specific antibody against CASK/CAMGUK
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CASK
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, CASK displays a transcription regulation function, CASK is expressed in rat brain where it binds to cell-surface proteins, CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, SH3 and guanylate kinase-like (GUK) domains, and induces the expression of specific genes, and is thought to be involved in signaling at neuronal synapses, and signaling, including Reelin, such as neurexin and syndecan, tumor suppression, which appears crucial for cerebrocortical development, which binds to a specific DNA sequence (the T-element), The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms LIN2 CAGH39 FGS4
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CASK/CAMGUK Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetCASK/CAMGUK
Short nameCASK/CAMGUK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, calcium/calmodulin-dependent serine protein kinase (MAGUK family)/CAMGUK (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CAGH39 and CAMGUK and CMG and FGS4 and LIN2 and MICPCH and MRXSNA and TNRC8, CASK and IDBG-57627 and ENSG00000147044 and 8573, CASK and IDBG-637908 and ENSBTAG00000020136 and 404149, Cask and IDBG-133241 and ENSMUSG00000031012 and 12361, nuclei, this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0004385 and guanylate kinase activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0005634 and nucleus and cellular component this GO :0005652 and nuclear lamina and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0010839 and negative regulation of keratinocyte proliferation and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016363 and nuclear matrix and cellular component this GO :0016772 and transferase activity, this GO :0004385: guanylate kinase activity, this GO :0004385: guanylate kinase activity and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005516: calmodulin binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005516: calmodulin binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0042043: neurexin family protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042043: neurexin family protein binding, transferring phosphorus-containing groups and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0042043 and neurexin family protein binding and molecular function this GO :0042734 and presynaptic membrane and cellular component this GO :0045202 and synapse and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046939 and nucleotide phosphorylation and biological process this GO :0060170 and ciliary membrane and cellular component this GO :0061045 and negative regulation of wound healing and biological process this GO :0070509 and calcium ion import and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :0090288 and negative regulation of cellular response to growth factor stimulus and biological process, calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Identity 1497
Gene CASK
Long gene name calcium/calmodulin dependent serine protein kinase
Synonyms gene TNRC8
Synonyms gene name trinucleotide repeat containing 8 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Locus Xp11, 4
Discovery year 1998-09-25
GenBank acession AF035582
Entrez gene record 8573
Pubmed identfication 9722958
RefSeq identity NM_003688
Classification Trinucleotide repeat containing Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000021378
Locus Specific Databases Mental Retardation database

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