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Caspase 14 Antibody

Caspase 14 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCaspase 14 Primary Polyclonal Antibody
Also known asCaspase 14 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCaspase 14
SpecificityThis is a highly specific antibody against Caspase 14
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range200-242/242
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase 14
Gene ID number23581
Swiss ProtP31944
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In vitro has a preference for the substate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF (PubMed:16854378, Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD (PubMed:24743736), Involved in processing of prosaposin in the epidermis (By similarity), Is the predominant caspase in epidermal stratum corneum (PubMed:15556625), May be involved in retinal pigment epithelium cell barrier function (PubMed:25121097), PubMed:19960512), Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity), Seems to play a role in keratinocyte differentiation and is required for cornification, Non-apoptotic caspase involved in epidermal differentiation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CASP-14, CASP14, Caspase-14
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCaspase 14
Short nameCaspase 14 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecaspase 14 (Antibody to)
Alternative techniqueantibodies
Identity 16446
Gene CARD14
Long gene name caspase recruitment domain family member 14
Synonyms gene PSORS2
Synonyms gene name member 14 , psoriasis susceptibility 2 caspase recruitment domain family
Synonyms CARMA2 BIMP2
Locus 17q25, 3
Discovery year 2002-09-19
GenBank acession AF322642
Entrez gene record 79092
Pubmed identfication 11278692 11356195 22521418
Classification Caspase recruitment domain containing Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000177549

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