Name : Caspase 3 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9106023683
| Long name | ALEXA FLUOR 488 Conjugated, Caspase 3 Polyclonal Antibody |
| Also known as | Anti-Caspase-3 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Caspase-3 |
| Specificity | This is a highly specific antibody against Caspase-3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 60-100/277 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase 3(Active) |
| Gene ID Number | 836 |
| Swiss Prot | P42574 |
| Tested applications | IF(ICC), IF(IHC-P), FCM |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Bovine, Goat, Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | -7 and -9, At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond, Cleaves and activates caspase-6, Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain, Involved in the cleavage of huntingtin, Triggers cell adhesion in sympathetic neurons through RET cleavage, Involved in the activation cascade of caspases responsible for apoptosis execution |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Caspase 3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Caspase 3 |
| Short name | Caspase 3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, caspase 3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 43777 |
| Gene | CASP1P3 |
| Long gene name | caspase 1 pseudogene 3 |
| Synonyms gene name | apoptosis-related cysteine peptidase pseudogene 3 , caspase 1 |
| Locus | 11q22, 3 |
| Discovery year | 2012-02-24 |
| Entrez gene record | 100422634 |
| RefSeq identity | NG_024409 |