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caspase-3 p12 subunit Antibody

caspase-3 p12 subunit Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namecaspase-3 p12 subunit Antibody
Also known ascaspase-3 p12 subunit Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigencaspase-3 p12 subunit
SpecificityThis is a highly specific antibody against caspase-3 p12 subunit
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human caspase-3 p12 subunit
Gene ID number836
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 7 and 9), 9 and 10), Alternative splicing of this gene results in two transcript variants which encode the same protein, Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176, Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e, Caspase 3 is the most extensively studied apoptotic protein among caspase family members, Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, Caspases 6, Caspases 8, Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells), In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e, PARP and DFF), The active Caspase 3 proteolytically cleaves and activates other caspases (e, The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme, as well as relevant targets in the cells (e, commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts), which is associated with neuronal death in Alzheimer's disease, The caspase family of cysteine proteases play a key role in apoptosis, g, g, g, g
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names APOPAIN, Apopain, CASP-3, CASP3, CASP3_HUMAN, CPP32, CPP32B, Caspase 3 apoptosis related cysteine protease, Caspase-3, Caspase3, Cysteine protease CPP32, Human cysteine protease CPP32 isoform alpha mRNA complete cds, PARP cleavage protease, Protein Yama, SCA 1, SCA-1, SCA1, SREBP cleavage activity 1, SREBP cleavage activity 1, Yama, Caspase-3 subunit p12
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways, Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation
Gene targetcaspase-3 p12 subunit
Short namecaspase-3 p12 subunit Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecaspase-3 p12 functionnal sequence (Antibody to)
Alternative techniqueantibodies

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