Name : Caspase 8 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7753713449
| Long name | Cy3 Conjugated, Caspase 8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Caspase 8 |
| Specificity | This is a highly specific antibody against Caspase 8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 430-482/482 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse Caspase-8 subunit p10 |
| Gene ID number | 12370 |
| Swiss Prot | O89110 |
| Tested applications | IF(ICC), IF(IHC-P) |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Ac-Asp-Glu-Val-Asp-|-AMC, Binding to the adapter molecule FADD recruits it to either receptor, CAP5 and CAP6) are likely retained in the DISC, CASP4, CASP6, CASP7, CASP9 and CASP1, Cleaves ADPRT, Cleaves and activates CASP3, Hydrolyzes the small-molecule substrate, Likely target for the cowpox virus CRMA death inhibitory protein, May participate in the GZMB apoptotic pathways, Proteolytic fragments of the N-terminal propeptide (termed CAP3, The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases, The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation, Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | CASP-8, Casp8, Caspase-8, FLICE, Mch5, MACH |
| Properties | 1 of the Caspase 8 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Caspase 8 Conjugated |
| Short name | Conjugated, Caspase 8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, caspase 8 (Antibody to) |
| Alternative technique | antibodies |