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Caspase-8 subunit p18 Antibody

Caspase-8 subunit p18 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCaspase-8 subunit p18 Antibody
Also known asCaspase-8 subunit p18 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCaspase-8 subunit p18
SpecificityThis is a highly specific antibody against Caspase-8 subunit p18
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range217-244/479
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase-8 subunit p18
Gene ID number841
Swiss ProtQ14790
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Ac-Asp-Glu-Val-Asp-|-AMC, Binding to the adapter molecule FADD recruits it to either receptor, CAP5 and CAP6) are likely retained in the DISC, CASP4, CASP6, CASP7, CASP9 and CASP10, Cleaves ADPRT, Cleaves and activates CASP3, Hydrolyzes the small-molecule substrate, Isoform 5, Likely target for the cowpox virus CRMA death inhibitory protein, May participate in the GZMB apoptotic pathways, Proteolytic fragments of the N-terminal propeptide (termed CAP3, The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases, The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex, Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ALPS2B, Apoptotic cysteine protease, Apoptotic protease Mch-5, CASP8, Casp-8, Caspase-8, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MACH, MCH5, MORT1-associated ced-3 homolog, CAP4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCaspase-8 subunit p18
Short nameCaspase-8 subunit p18 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecaspase-8 functionnal sequence p18 (Antibody to)
Alternative techniqueantibodies

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