Name : Caspase-9 (Thr125) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN8606210997
| Long name | Caspase-9 (Thr125) Primary Polyclonal Antibody |
| Also known as | Caspase-9 (Thr125) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Caspase-9 Thr125 |
| Specificity | This phosphorylation site is homologous to that of Thr163 in Mouse, This is a highly specific antibody against Caspase-9 Thr125 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr125 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 100-150/416 |
| Subcellular location | Mitochondrion, Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human Caspase-9 around the phosphorylation site of Thr125 |
| Gene ID number | 842 |
| Swiss Prot | P55211 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3, Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9, Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, Proteolytically cleaves poly(ADP-ribose) polymerase (PARP), Involved in the activation cascade of caspases responsible for apoptosis execution |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, Caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, PPP1R56, MCH6 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Caspase-9 (Thr125) |
| Short name | Caspase-9 (Thr125) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | caspase-9 (Thr125) (Antibody to) |
| Alternative technique | antibodies |