Name : Caspase-9 (Tyr153) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN3607422061
| Long name | ALEXA FLUOR 488 Conjugated, Caspase-9 (Tyr153) Polyclonal Antibody |
| Also known as | Anti-Caspase-9 Tyr153 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Caspase-9 Tyr153 |
| Specificity | This is a highly specific antibody against Caspase-9 Tyr153 |
| Modification | Phosphorylation |
| Modification Site | Tyr153 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153 |
| Gene ID Number | 842 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | BclXL, Caspase 3, Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin, Caspase 9 is inhibited by the dominant negative isoform, Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6, ProCaspase 9 has been reported to be approximately 47 kD, This caspase becomes activated when recruited to Apaf1/cytochrome c complex, This caspase is active as a heterotetramer and has been reported to have two isoforms, This caspase is present in the cytosol and, XIAP, and Livin, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain, and following cleavage by Apaf1, apoptotic protease Mch6, cIAP1, cIAP2, granzyme B, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits, translocates to the mitochondria, upon activation, Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch 6, Apoptotic protease activating factor 3, CASP 9, CASP9, CASP9_HUMAN, Caspase 9 Dominant Negative, Caspase 9 precursor, Caspase 9c, Caspase9, EC 3, ICE LAP6, ICE like apoptotic protease 6, MCH6 antibody RNCASP9, 4, 22, APAF 3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Caspase-9 (Tyr153) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Caspase-9 (Tyr153) |
| Short name | Caspase-9 (Tyr153) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, caspase-9 (Tyr153) (Antibody to) |
| Alternative technique | antibodies |