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Caspase-9 (Tyr153) Antibody, Biotin Conjugated

Caspase-9 (Tyr153) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Caspase-9 (Tyr153) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCaspase-9 Tyr153
SpecificityThis is a highly specific antibody against Caspase-9 Tyr153
ModificationPhosphorylation
Modification siteTyr153
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153
Gene ID number842
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BclXL, Caspase 3, Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin, Caspase 9 is inhibited by the dominant negative isoform, Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6, ProCaspase 9 has been reported to be approximately 47 kD, This caspase becomes activated when recruited to Apaf1/cytochrome c complex, This caspase is active as a heterotetramer and has been reported to have two isoforms, This caspase is present in the cytosol and, XIAP, and Livin, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain, and following cleavage by Apaf1, apoptotic protease Mch6, cIAP1, cIAP2, granzyme B, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits, translocates to the mitochondria, upon activation, Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch 6, Apoptotic protease activating factor 3, CASP 9, CASP9, CASP9_HUMAN, Caspase 9 Dominant Negative, Caspase 9 precursor, Caspase 9c, Caspase9, EC 3, ICE LAP6, ICE like apoptotic protease 6, MCH6 antibody RNCASP9, 4, 22, APAF 3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCaspase-9 (Tyr153) Conjugated
Short name Conjugated, Caspase-9 (Tyr153) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, caspase-9 (Tyr153) (Antibody to)
Alternative techniqueantibodies

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