Name : Caspase-9 (Tyr153) Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN4914725650
| Long name | Cy5, 5 Conjugated, Caspase-9 (Tyr153) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Caspase-9 Tyr153 |
| Specificity | This is a highly specific antibody against Caspase-9 Tyr153 |
| Modification | Phosphorylation |
| Modification site | Tyr153 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153 |
| Gene ID number | 842 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BclXL, Caspase 3, Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin, Caspase 9 is inhibited by the dominant negative isoform, Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6, ProCaspase 9 has been reported to be approximately 47 kD, This caspase becomes activated when recruited to Apaf1/cytochrome c complex, This caspase is active as a heterotetramer and has been reported to have two isoforms, This caspase is present in the cytosol and, XIAP, and Livin, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain, and following cleavage by Apaf1, apoptotic protease Mch6, cIAP1, cIAP2, granzyme B, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits, translocates to the mitochondria, upon activation, Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch 6, Apoptotic protease activating factor 3, CASP 9, CASP9, CASP9_HUMAN, Caspase 9 Dominant Negative, Caspase 9 precursor, Caspase 9c, Caspase9, EC 3, ICE LAP6, ICE like apoptotic protease 6, MCH6 antibody RNCASP9, 4, 22, APAF 3 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | Caspase-9 (Tyr153) Conjugated |
| Short name | Conjugated, Caspase-9 (Tyr153) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, caspase-9 (Tyr153) (Antibody to) |
| Alternative technique | antibodies |