Name : Cathepsin C/DPP1 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4447165830
| Long name | ALEXA FLUOR 488 Conjugated, Cathepsin C/DPP1 Polyclonal Antibody |
| Also known as | Anti-Cathepsin C/DPP1 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Cathepsin C/DPP1 |
| Specificity | This is a highly specific antibody against Cathepsin C/DPP1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DPP-I |
| Gene ID Number | 1075 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, It is composed of a dimer of disulfide-linked heavy and light chains, Multiple transcript variants encoding different isoforms have been found for this gene, This enzyme requires chloride ions for activity and can degrade glucagon, [provided by RefSeq], a member of the peptidase C1 family, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme, both produced from a single protein precursor, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells, The protein encoded by this gene |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | DPP1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cathepsin C/DPP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene | CTSC |
| Gene target | Cathepsin C/DPP1 |
| Short name | Cathepsin C/DPP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Cathepsin C/DPP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2528 |
| Long gene name | cathepsin C |
| Synonyms gene | PLS PALS |
| Synonyms name | dipeptidyl peptidase 1 |
| Locus | 11q14, 2 |
| Discovery year | 1995-11-08 |
| GenBank acession | AK223038 |
| Entrez gene record | 1075 |
| Pubmed identfication | 7649281 9092576 |
| RefSeq identity | NM_001814 |
| Classification | Cathepsins |
| Havana BLAST/BLAT | OTTHUMG00000167290 |
| Locus Specific Databases | CTSCbase: Mutation registry for Papillon-Lefevre syndrome LRG_50 |