Name : CBL, Mouse Monoclonal antibody-; Clone: 6D12
Supplier : ACCURATE MONOCLONALS
Price :0
SKU : GEN2809131134
| Alternative name 1 | Clone: 6D12, Mab anti-, CBL |
| Alternative name 2 | Clone: 6D12, Mab antibody-, CBL |
| Alternative name 3 | Clone: 6D12, Mab antibody-, CBL |
| Alternative name 4 | anti-CBL Clone: 6D12 |
| Alternative name 5 | CBL Clone: 6D12 |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | Monoclonal 6D12, CBL |
| Short name | Mouse Monoclonal antibody- Clone: 6D12, CBL |
| Technique | Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species | Mouses, Mouse |
| Alternative name | E3 ubiquitin protein ligase, Mouse monoclonal (Antibody to)-, clonality: 6D12, Cbl proto-oncogene |
| Alternative technique | murine |
| Alternative to gene target | C-CBL and CBL2 and FRA11B and NSLL and RNF55, CBL and IDBG-631730 and ENSBTAG00000006817 and 527418, CBL and IDBG-74417 and ENSG00000110395 and 867, Cbl and IDBG-155970 and ENSMUSG00000034342 and 12402, DNA-templated and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016600 and flotillin complex and cellular component this GO :0016874 and ligase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046875 and ephrin receptor binding and molecular function this GO :0048260 and positive regulation of receptor-mediated endocytosis and biological process, E3 ubiquitin protein ligase, ephrin receptor binding, nuclei, this GO :0001784 and phosphotyrosine binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0001784: phosphotyrosine binding, this GO :0001784: phosphotyrosine binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004842: ubiquitin-protein transferase activity and also this GO :0004871: signal transducer activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0017124: SH3 domain binding and also this GO :0046872: metal ion binding and also this GO :0046875: ephrin receptor binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004871: signal transducer activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0017124: SH3 domain binding, this GO :0046872: metal ion binding, this GO :0046875: ephrin receptor binding, Cbl proto-oncogene |
| Identity | 1541 |
| Gene | CBL |
| Long gene name | Cbl proto-oncogene |
| Synonyms gene | CBL2 |
| Synonyms gene name | Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase |
| Synonyms | RNF55 c-Cbl |
| Synonyms name | oncogene CBL2 |
| Locus | 11q23, 3 |
| Discovery year | 1989-06-30 |
| GenBank acession | X57110 |
| Entrez gene record | 867 |
| Pubmed identfication | 2013228 |
| RefSeq identity | NM_005188 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000166170 |
| Locus Specific Databases | LRG_608 |