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CBL2 (Tyr674) Antibody, FITC Conjugated

CBL2 (Tyr674) Antibody, FITC Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name FITC Conjugated, CBL2 (Tyr674) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCBL2 Tyr674
SpecificityThis is a highly specific antibody against CBL2 Tyr674
ModificationPhosphorylation
Modification siteTyr674
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr674
Gene ID number867
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as an E3 ubiquitin-protein ligase, Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface, EGF and CSF1, Recognizes activated receptor tyrosine kinases, and terminates signaling, and then transfers it to substrates promoting their degradation by the proteasome, including PDGFA, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, Participates in signal transduction in hematopoietic cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms RNF55 c-Cbl
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCBL2 (Tyr674) Conjugated
Short name FITC Conjugated, CBL2 (Tyr674) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CBL2 (Tyr674) (Antibody to)
Alternative techniqueantibodies
Identity 1541
Gene CBL
Long gene name Cbl proto-oncogene
Synonyms gene CBL2
Synonyms gene name Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms name oncogene CBL2
Locus 11q23, 3
Discovery year 1989-06-30
GenBank acession X57110
Entrez gene record 867
Pubmed identfication 2013228
RefSeq identity NM_005188
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000166170
Locus Specific Databases LRG_608

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