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CBL2 (Tyr731) Antibody, ALEXA FLUOR 647

CBL2 (Tyr731) Antibody, ALEXA FLUOR 647 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, CBL2 (Tyr731) Polyclonal Antibody
Also known asAnti-CBL2 Tyr731 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCBL2 Tyr731
SpecificityThis is a highly specific antibody against CBL2 Tyr731
ModificationPhosphorylation
Modification SiteTyr731
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr731
Gene ID Number867
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen An additional mechanism to attenuate receptor signaling is thought to be achieved by CBLâ, In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling, Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families, The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, such as PI 3K and Vav, thus attenuating the signal of receptors, &euro, &trade, The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice, s interaction with downstream targets of tyrosine kinases
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms RNF55 c-Cbl
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CBL2 (Tyr731) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetCBL2 (Tyr731)
Short nameCBL2 (Tyr731) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, CBL2 (Tyr731) (Antibody to)
Alternative techniqueantibodies
Identity 1541
Gene CBL
Long gene name Cbl proto-oncogene
Synonyms gene CBL2
Synonyms gene name Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms name oncogene CBL2
Locus 11q23, 3
Discovery year 1989-06-30
GenBank acession X57110
Entrez gene record 867
Pubmed identfication 2013228
RefSeq identity NM_005188
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000166170
Locus Specific Databases LRG_608

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