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CBX4 Antibody, Biotin Conjugated

CBX4 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CBX4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCBX4
SpecificityThis is a highly specific antibody against CBX4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range415-445/560
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human CBX4
Gene ID number8535
Swiss ProtO00257
Tested applicationsWB
Recommended dilutionsWB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Component of a Polycomb group (PcG) multiprotein PRC1-like complex, Involved in the sumoylation of HNRNPK, Monosumoylates ZNF131, PcG PRC1 complex acts via chromatin remodeling and modification of histones, a complex class required to maintain the transcriptionally repressive state of many genes, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression, including Hox genes, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, throughout development, E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms hPC2 PC2 NBP16
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCBX4 Conjugated
Short name Conjugated, CBX4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, chromobox homolog 4 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CBX4 and IDBG-642715 and ENSBTAG00000009782 and, CBX4 and IDBG-71254 and ENSG00000141582 and 8535, Cbx4 and IDBG-214671 and ENSMUSG00000039989 and 12418, DNA-templated and biological process this GO :0016568 and chromatin modification and biological process this GO :0016604 and nuclear body and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0016874 and ligase activity and molecular function this GO :0016925 and protein sumoylation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0031519 and PcG protein complex and cellular component this GO :0032183 and SUMO binding and molecular function this GO :0035064 and methylated histone binding and molecular function this GO :0035102 and PRC1 complex and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0051219 and phosphoprotein binding and molecular function, NBP16 and PC2, nuclei, phosphoprotein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, this GO :0003682: chromatin binding, this GO :0003682: chromatin binding and also this GO :0003714: transcription corepressor activity and also this GO :0003727: single-stranded RNA binding and also this GO :0005515: protein binding and also this GO :0016874: ligase activity and also this GO :0019899: enzyme binding and also this GO :0032183: SUMO binding and also this GO :0035064: methylated histone binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0051219: phosphoprotein binding, this GO :0003714: transcription corepressor activity, this GO :0003727: single-stranded RNA binding, this GO :0005515: protein binding, this GO :0016874: ligase activity, this GO :0019899: enzyme binding, this GO :0032183: SUMO binding, this GO :0035064: methylated histone binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0051219: phosphoprotein binding, chromobox homolog 4
Identity 1554
Gene CBX4
Long gene name chromobox 4
Synonyms gene name chromobox homolog 4 (Drosophila Pc class) chromobox homolog 4
Synonyms name NS5ATP1-binding protein 16 Pc class 2 homolog (Drosophila)
Locus 17q25, 3
Discovery year 1998-10-20
GenBank acession AF013956
Entrez gene record 8535
Pubmed identfication 9315667
RefSeq identity NM_003655
Classification Chromobox family
Havana BLAST/BLAT OTTHUMG00000150415

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