Name : CCL21/6Ckine Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4154688704
| Long name | CCL21/6Ckine Primary Polyclonal Antibody |
| Also known as | CCL21/6Ckine PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CCL21/6Ckine |
| Specificity | This is a highly specific antibody against CCL21/6Ckine |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 70-120/134 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCL21 |
| Gene ID number | 6366 |
| Swiss Prot | O00585 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4, Chemotactic in vitro for thymocytes and activated T-cells, May play a role in mediating homing of lymphocytes to secondary lymphoid organs, Shows preferential activity towards naive T-cells, but not for B-cells, macrophages, or neutrophils, Inhibits hemopoiesis and stimulates chemotaxis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 6Ckine, Beta-chemokine exodus-2, C-C motif chemokine 21, CCL21, CKb9, SCYA21, SLC, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21, TCA4, UNQ784/PRO1600, ECL |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CCL21/6Ckine |
| Short name | CCL21/6Ckine Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-C motif) ligand 21/6Ckine (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | 6Ckine and CKb9 and ECL and SCYA21 and SLC and TCA4, BT, CCL21 and IDBG-61074 and ENSG00000137077 and 6366, Extracellular, chemokine receptor binding, this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0010560 and positive regulation of glycoprotein biosynthetic process and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0031295 and T cell costimulation and biological process this GO :0031529 and ruffle organization and biological process this GO :0031732 and CCR7 chemokine receptor binding and molecular function this GO :0032862 and activation of Rho GTPase activity and biological process this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0034695 and response to prostaglandin E and biological process this GO :0035759 and mesangial cell-matrix adhesion and biological process this GO :0042379 and chemokine receptor binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0048260 and positive regulation of receptor-mediated endocytosis and biological process this GO :0048469 and cell maturation and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0097026 and dendritic cell dendrite assembly and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2000406 and positive regulation of T cell migration and biological process this GO :2000529 and positive regulation of myeloid dendritic cell chemotaxis and biological process this GO :2000548 and negative regulation of dendritic cell dendrite assembly and biological process, this GO :0008009: chemokine activity, this GO :0008009: chemokine activity and also this GO :0031732: CCR7 chemokine receptor binding and also this GO :0042379: chemokine receptor binding, this GO :0031732: CCR7 chemokine receptor binding, this GO :0042379: chemokine receptor binding, 26536 and IDBG-635977 and ENSBTAG00000010161 and 511112, chemokine (C-C motif) ligand 21 |
| Identity | 10620 |
| Gene | CCL21 |
| Long gene name | C-C motif chemokine ligand 21 |
| Synonyms gene | SCYA21 |
| Synonyms gene name | member 21 chemokine (C-C motif) ligand 21 , small inducible cytokine subfamily A (Cys-Cys) |
| Synonyms | SLC exodus-2 TCA4 CKb9 6Ckine ECL |
| Synonyms name | beta chemokine exodus-2 secondary lymphoid tissue chemokine Efficient Chemoattractant for Lymphocytes |
| Locus | 9p13, 3 |
| Discovery year | 1997-04-10 |
| GenBank acession | AB002409 |
| Entrez gene record | 6366 |
| Pubmed identfication | 9235955 |
| RefSeq identity | NM_002989 |
| Classification | Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT | OTTHUMG00000019838 |