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CCL5 Antibody / RANTES

CCL5 Antibody / RANTES size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCCL5 / RANTES
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutions1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0
NotesOptimal dilution of the CCL5 antibody should be determined by the researcher
Intented useThis CCL5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P13501
PurityAntigen affinity
Description Alternative splicing results in multiple transcript variants that encode different isoforms, Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes, It causes the release of histamine from basophils and activates eosinophils, It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), It is also known as RANTES, The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide, This chemokine, This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells, This gene is one of several chemokine genes clustered on the q-arm of chromosome 17, a member of the CC subfamily, and it suppresses in vitro replication of the R5 strains of HIV-1, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils, which use CCR5 as a coreceptor, Chemokine (C-C motif) ligand 5 is a protein which in humans is encoded by the CCL5 gene
ImmunogenAmino acids 26-91 of human /CCL5RANTES were used as the immunogen for the CCL5 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCL5 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCCL5 / RANTES
Short nameCCL5 Antibody / RANTES
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCCL5 (Antibody to) / RANTES
Alternative techniqueantibodies
Identity 10632
Gene CCL5
Long gene name C-C motif chemokine ligand 5
Synonyms gene D17S136E SCYA5
Synonyms gene name small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5
Synonyms RANTES SISd TCP228 MGC17164
Synonyms name T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed
Locus 17q12
Discovery year 1990-07-05
GenBank acession AF043341
Entrez gene record 6352
Pubmed identfication 1691736
RefSeq identity NM_002985
Classification Endogenous ligands Chemokine ligands
Havana BLAST/BLAT OTTHUMG00000188396

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