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CCL5/RANTES Antibody

CCL5/RANTES Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCCL5/RANTES Primary Polyclonal Antibody
Also known asCCL5/RANTES PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCCL5/RANTES
SpecificityThis is a highly specific antibody against CCL5/RANTES
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range71-89/91
Subcellular location Helical, Secreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCL5
Gene ID number6352
Swiss ProtP13501
Tested Applications IF(IHC-P), IHC-P, FCM
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100)
Cross reactivity Bovine, Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Akt and MAP kinases, By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485), CCR3, CCR4 and CCR5, Causes the release of histamine from basophils and activates eosinophils, HIV-2, May activate several chemokine receptors including CCR1, May also be an agonist of the G protein-coupled receptor GPR75, One of the major HIV-suppressive factors produced by CD8+ T-cells, PubMed:13864, PubMed:15923218), PubMed:8525373, PubMed:9516414, Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection, The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, Together with GPR75, and simian immunodeficiency virus (SIV), may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, memory T-helper cells and eosinophils, stimulating inositol trisphosphate production and calcium mobilization through its activation, Chemoattractant for blood monocytes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-C motif chemokine 5, CCL5, D17S136E, Eosinophil chemotactic cytokine, RANTES, SCYA5, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, T-cell-specific protein RANTES, TCP228, eoCP, SISd
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCCL5/RANTES
Short nameCCL5/RANTES Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCCL5/RANTES (Antibody to)
Alternative techniqueantibodies
Identity 10632
Gene CCL5
Long gene name C-C motif chemokine ligand 5
Synonyms gene D17S136E SCYA5
Synonyms gene name small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5
Synonyms RANTES SISd TCP228 MGC17164
Synonyms name T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed
Locus 17q12
Discovery year 1990-07-05
GenBank acession AF043341
Entrez gene record 6352
Pubmed identfication 1691736
RefSeq identity NM_002985
Classification Endogenous ligands Chemokine ligands
Havana BLAST/BLAT OTTHUMG00000188396

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