Name : CCL5/RANTES Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5924356879
| Long name | Cy5, 5 Conjugated, CCL5/RANTES Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CCL5/RANTES |
| Specificity | This is a highly specific antibody against CCL5/RANTES |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 71-89/91 |
| Subcellular location | Helical, Secreted |
| Source | KLH conjugated synthetic peptide derived from human CCL5 |
| Gene ID number | 6352 |
| Swiss Prot | P13501 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Bovine, Mouse, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Akt and MAP kinases, By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485), CCR3, CCR4 and CCR5, Causes the release of histamine from basophils and activates eosinophils, HIV-2, May activate several chemokine receptors including CCR1, May also be an agonist of the G protein-coupled receptor GPR75, One of the major HIV-suppressive factors produced by CD8+ T-cells, PubMed:13864, PubMed:15923218), PubMed:8525373, PubMed:9516414, Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection, The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, Together with GPR75, and simian immunodeficiency virus (SIV), may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, memory T-helper cells and eosinophils, stimulating inositol trisphosphate production and calcium mobilization through its activation, Chemoattractant for blood monocytes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | RANTES SISd TCP228 MGC17164 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | CCL5/RANTES Conjugated |
| Short name | Conjugated, CCL5/RANTES Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, CCL5/RANTES (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10632 |
| Gene | CCL5 |
| Long gene name | C-C motif chemokine ligand 5 |
| Synonyms gene | D17S136E SCYA5 |
| Synonyms gene name | small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5 |
| Synonyms name | T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed |
| Locus | 17q12 |
| Discovery year | 1990-07-05 |
| GenBank acession | AF043341 |
| Entrez gene record | 6352 |
| Pubmed identfication | 1691736 |
| RefSeq identity | NM_002985 |
| Classification | Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT | OTTHUMG00000188396 |