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CCL5/RANTES Antibody, Cy5.5 Conjugated

CCL5/RANTES Antibody, Cy5.5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5, 5 Conjugated, CCL5/RANTES Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCCL5/RANTES
SpecificityThis is a highly specific antibody against CCL5/RANTES
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range71-89/91
Subcellular location Helical, Secreted
SourceKLH conjugated synthetic peptide derived from human CCL5
Gene ID number6352
Swiss ProtP13501
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Bovine, Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Akt and MAP kinases, By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485), CCR3, CCR4 and CCR5, Causes the release of histamine from basophils and activates eosinophils, HIV-2, May activate several chemokine receptors including CCR1, May also be an agonist of the G protein-coupled receptor GPR75, One of the major HIV-suppressive factors produced by CD8+ T-cells, PubMed:13864, PubMed:15923218), PubMed:8525373, PubMed:9516414, Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection, The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, Together with GPR75, and simian immunodeficiency virus (SIV), may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, memory T-helper cells and eosinophils, stimulating inositol trisphosphate production and calcium mobilization through its activation, Chemoattractant for blood monocytes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms RANTES SISd TCP228 MGC17164
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetCCL5/RANTES Conjugated
Short name Conjugated, CCL5/RANTES Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, CCL5/RANTES (Antibody to)
Alternative techniqueantibodies
Identity 10632
Gene CCL5
Long gene name C-C motif chemokine ligand 5
Synonyms gene D17S136E SCYA5
Synonyms gene name small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5
Synonyms name T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed
Locus 17q12
Discovery year 1990-07-05
GenBank acession AF043341
Entrez gene record 6352
Pubmed identfication 1691736
RefSeq identity NM_002985
Classification Endogenous ligands Chemokine ligands
Havana BLAST/BLAT OTTHUMG00000188396

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