| Long name | CCR2 Primary Polyclonal Antibody |
| Also known as | CCR2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CCR2 |
| Specificity | This is a highly specific antibody against CCR2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse CCR-2 |
| Gene ID number | 729230 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Mar 2009], Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors, The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase, This gene is located in the chemokine receptor gene cluster region, Two alternatively spliced transcript variants are expressed by the gene, [provided by RefSeq, a chemokine which specifically mediates monocyte chemotaxis, This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C-C CKR-2, CC-CKR-2, CCR-2, CCR2, CMKBR2, MCP-1-R, Monocyte chemoattractant protein 1 receptor, C-C chemokine receptor type 2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CCR2 |
| Short name | CCR2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-C motif) receptor 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CCR2 and IDBG-30182 and ENSG00000121807 and 729230, Plasma membranes, alpha-beta T cell extravasation and biological process this GO :2000464 and positive regulation of astrocyte chemotaxis and biological process this GO :2000473 and positive regulation of hematopoietic stem cell migration and biological process, protein homodimerization activity, this GO :0001974 and blood vessel remodeling and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002827 and positive regulation of T-helper 1 type immune response and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007194 and negative regulation of adenylate cyclase activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009611 and response to wounding and biological process this GO :0010574 and regulation of vascular endothelial growth factor production and biological process this GO :0010820 and positive regulation of T cell chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019725 and cellular homeostasis and biological process this GO :0030425 and dendrite and cellular component this GO :0031727 and CCR2 chemokine receptor binding and molecular function this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0035705 and T-helper 17 cell chemotaxis and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043310 and negative regulation of eosinophil degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0090265 and positive regulation of immune complex clearance by monocytes and macrophages and biological process this GO :2000439 and positive regulation of monocyte extravasation and biological process this GO :2000451 and positive regulation of CD8-positive, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0016493: C-C chemokine receptor activity and also this GO :0031727: CCR2 chemokine receptor binding and also this GO :0042803: protein homodimerization activity, this GO :0004950: chemokine receptor activity, this GO :0016493: C-C chemokine receptor activity, this GO :0031727: CCR2 chemokine receptor binding, this GO :0042803: protein homodimerization activity, 63814 and IDBG-647810 and ENSBTAG00000013586 and 539002, chemokine (C-C motif) receptor 2 |
| Identity | 1603 |
| Gene | CCR2 |
| Long gene name | C-C motif chemokine receptor 2 |
| Synonyms gene | CMKBR2 |
| Synonyms gene name | chemokine (C-C motif) receptor 2 |
| Synonyms | CC-CKR-2 CKR2 MCP-1-R CD192 FLJ78302 |
| Locus | 3p21, 31 |
| Discovery year | 1995-05-30 |
| Entrez gene record | 729230 |
| Pubmed identfication | 8146186 |
| RefSeq identity | NM_000647 |
| Classification | CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT | OTTHUMG00000156466 |
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