| Long name | ALEXA FLUOR 647 Conjugated, CCR2 Polyclonal Antibody |
| Also known as | Anti-CCR2 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CCR2 |
| Specificity | This is a highly specific antibody against CCR2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse CCR-2 |
| Gene ID Number | 729230 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Mar 2009], Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors, The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase, This gene is located in the chemokine receptor gene cluster region, Two alternatively spliced transcript variants are expressed by the gene, [provided by RefSeq, a chemokine which specifically mediates monocyte chemotaxis, This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | CC-CKR-2 CKR2 MCP-1-R CD192 FLJ78302 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CCR2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | CCR2 |
| Short name | CCR2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, chemokine (C-C motif) receptor 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CCR2 and IDBG-30182 and ENSG00000121807 and 729230, Plasma membranes, alpha-beta T cell extravasation and biological process this GO :2000464 and positive regulation of astrocyte chemotaxis and biological process this GO :2000473 and positive regulation of hematopoietic stem cell migration and biological process, protein homodimerization activity, this GO :0001974 and blood vessel remodeling and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002827 and positive regulation of T-helper 1 type immune response and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007194 and negative regulation of adenylate cyclase activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009611 and response to wounding and biological process this GO :0010574 and regulation of vascular endothelial growth factor production and biological process this GO :0010820 and positive regulation of T cell chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019725 and cellular homeostasis and biological process this GO :0030425 and dendrite and cellular component this GO :0031727 and CCR2 chemokine receptor binding and molecular function this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0035705 and T-helper 17 cell chemotaxis and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043310 and negative regulation of eosinophil degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0090265 and positive regulation of immune complex clearance by monocytes and macrophages and biological process this GO :2000439 and positive regulation of monocyte extravasation and biological process this GO :2000451 and positive regulation of CD8-positive, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0016493: C-C chemokine receptor activity and also this GO :0031727: CCR2 chemokine receptor binding and also this GO :0042803: protein homodimerization activity, this GO :0004950: chemokine receptor activity, this GO :0016493: C-C chemokine receptor activity, this GO :0031727: CCR2 chemokine receptor binding, this GO :0042803: protein homodimerization activity, 63814 and IDBG-647810 and ENSBTAG00000013586 and 539002, chemokine (C-C motif) receptor 2 |
| Identity | 1603 |
| Gene | CCR2 |
| Long gene name | C-C motif chemokine receptor 2 |
| Synonyms gene | CMKBR2 |
| Synonyms gene name | chemokine (C-C motif) receptor 2 |
| Locus | 3p21, 31 |
| Discovery year | 1995-05-30 |
| Entrez gene record | 729230 |
| Pubmed identfication | 8146186 |
| RefSeq identity | NM_000647 |
| Classification | CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT | OTTHUMG00000156466 |
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