| Long name | CCR4 Primary Polyclonal Antibody |
| Also known as | CCR4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CCR4 |
| Specificity | This is a highly specific antibody against CCR4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 200-250/360 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCR-4 |
| Gene ID number | 1233 |
| Swiss Prot | P51679 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates, In the CNS, The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system, could mediate hippocampal-neuron survival, High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CCR4, CD194, CMKBR4, ChemR13, HGCN:14099, K5-5, CKR4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CCR4 |
| Short name | CCR4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-C motif) receptor 4 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | C-C chemokine receptor activity, CC-CKR-4 and CD194 and ChemR13 and CKR4 and CMKBR4 and HGCN:14099 and K5-5, CCR4 and IDBG-23908 and ENSG00000183813 and 1233, CCR4 and IDBG-644121 and ENSBTAG00000034883 and 100851774, Ccr4 and IDBG-203512 and ENSMUSG00000047898 and 12773, Cell surfaces, this GO :0001764 and neuron migration and biological process this GO :0002507 and tolerance induction and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0009314 and response to radiation and biological process this GO :0009617 and response to bacterium and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0046677 and response to antibiotic and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0016493: C-C chemokine receptor activity, this GO :0004950: chemokine receptor activity, this GO :0016493: C-C chemokine receptor activity, 408019, chemokine (C-C motif) receptor 4 |
| Identity | 14099 |
| Gene | CNOT6 |
| Long gene name | CCR4-NOT transcription complex subunit 6 |
| Synonyms gene name | CCR4-NOT transcription complex, subunit 6 |
| Synonyms | CCR4 KIAA1194 Ccr4a |
| Locus | 5q35, 3 |
| Discovery year | 2001-03-30 |
| GenBank acession | AB033020 |
| Entrez gene record | 57472 |
| Pubmed identfication | 11889047 |
| RefSeq identity | NM_015455 |
| Classification | CCR4-NOT transcription complex |
| Havana BLAST/BLAT | OTTHUMG00000130935 |
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