Name : CCR5/CD195 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9284418648
| Long name | CCR5/CD195 Primary Polyclonal Antibody |
| Also known as | CCR5/CD195 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CCR5/CD195 |
| Specificity | This is a highly specific antibody against CCR5/CD195 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 204-233/352 |
| Subcellular location | Helical, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCR-5 |
| Gene ID number | 1234 |
| Swiss Prot | P51681 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level, May play a role in the control of granulocytic lineage proliferation or differentiation, Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCCKR5, CCR-5, CCR5, CD195, CHEMR13, CKR-5, CMKBR5, HIV-1 fusion coreceptor, IDDM22, CKR5 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CCR5/CD195 |
| Short name | CCR5/CD195 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-C motif) receptor 5 (gene/pseudogene)/CD195 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017, Cell surfaces, chemokine (C-C motif) ligand 5 binding, this GO :0000165 and MAPK cascade and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0003779 and actin binding and molecular function this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006816 and calcium ion transport and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0014808 and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0019957 and C-C chemokine binding and molecular function this GO :0023052 and signaling and biological process this GO :0030260 and entry into host cell and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070723 and response to cholesterol and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071791 and chemokine (C-C motif) ligand 5 binding and molecular function, this GO :0003779: actin binding, this GO :0003779: actin binding and also this GO :0004435: phosphatidylinositol phospholipase C activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0005515: protein binding and also this GO :0015026: coreceptor activity and also this GO :0016493: C-C chemokine receptor activity and also this GO :0019957: C-C chemokine binding and also this GO :0071791: chemokine (C-C motif) ligand 5 binding, this GO :0004435: phosphatidylinositol phospholipase C activity, this GO :0004930: G-protein coupled receptor activity, this GO :0004950: chemokine receptor activity, this GO :0005515: protein binding, this GO :0015026: coreceptor activity, this GO :0016493: C-C chemokine receptor activity, this GO :0019957: C-C chemokine binding, this GO :0071791: chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Identity | 1606 |
| Gene | CCR5 |
| Long gene name | C-C motif chemokine receptor 5 (gene/pseudogene) |
| Synonyms gene | CMKBR5 |
| Synonyms gene name | chemokine (C-C motif) receptor 5 chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Synonyms | CKR-5 CC-CKR-5 CKR5 CD195 IDDM22 |
| Locus | 3p21, 31 |
| Discovery year | 1996-05-15 |
| Entrez gene record | 1234 |
| Pubmed identfication | 8639485 |
| RefSeq identity | NM_000579 |
| Classification | CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT | OTTHUMG00000133481 |