Name : CCR6 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN5923773918
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CCR6 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the CCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This CCR6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P51684 |
| Purity | Antigen affinity |
| Description | Additionally, As the receptor for MIP-3-alpha, CCR6 are markedly upregulated in psoriasis, CCR6 gene is located at 6q27, Unlike most chemokine receptor genes, Weakly expressed as a 4-kb transcript in spleen, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors, it is encoded by more than 1 exon, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 |
| Immunogen | An amino acid sequence from the C-terminus of human CCR6 (RQTSETADNDNASSFTM) was used as the immunogen for this CCR6 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCR6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CCR6 |
| Short name | CCR6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-C motif) receptor 6 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, C-C chemokine receptor activity, CCR6 and IDBG-99015 and ENSG00000112486 and 1235, Ccr6 and IDBG-135484 and ENSMUSG00000040899 and 12458, Plasma membranes, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004872 and receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0006959 and humoral immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0016493: C-C chemokine receptor activity, this GO :0004930: G-protein coupled receptor activity, this GO :0004950: chemokine receptor activity, this GO :0016493: C-C chemokine receptor activity, 106551 and IDBG-647064 and ENSBTAG00000014496 and 519716, chemokine (C-C motif) receptor 6 |
| Identity | 1607 |
| Gene | CCR6 |
| Long gene name | C-C motif chemokine receptor 6 |
| Synonyms gene | STRL22 |
| Synonyms gene name | chemokine (C-C motif) receptor 6 |
| Synonyms | CKR-L3 GPR-CY4 CMKBR6 GPR29 DRY-6 DCR2 BN-1 CD196 |
| Locus | 6q27 |
| Discovery year | 1997-04-21 |
| GenBank acession | U68030 |
| Entrez gene record | 1235 |
| Pubmed identfication | 8886020 |
| Classification | CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT | OTTHUMG00000016015 |