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CCR6 Antibody

CCR6 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCCR6
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the CCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis CCR6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P51684
PurityAntigen affinity
Description Additionally, As the receptor for MIP-3-alpha, CCR6 are markedly upregulated in psoriasis, CCR6 gene is located at 6q27, Unlike most chemokine receptor genes, Weakly expressed as a 4-kb transcript in spleen, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors, it is encoded by more than 1 exon, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization, lymph nodes, peripheral blood lymphocytes and appendix, CCR6
ImmunogenAn amino acid sequence from the C-terminus of human CCR6 (RQTSETADNDNASSFTM) was used as the immunogen for this CCR6 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCR6 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCCR6
Short nameCCR6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namechemokine (C-C motif) receptor 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, C-C chemokine receptor activity, CCR6 and IDBG-99015 and ENSG00000112486 and 1235, Ccr6 and IDBG-135484 and ENSMUSG00000040899 and 12458, Plasma membranes, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004872 and receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0006959 and humoral immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0016493: C-C chemokine receptor activity, this GO :0004930: G-protein coupled receptor activity, this GO :0004950: chemokine receptor activity, this GO :0016493: C-C chemokine receptor activity, 106551 and IDBG-647064 and ENSBTAG00000014496 and 519716, chemokine (C-C motif) receptor 6
Identity 1607
Gene CCR6
Long gene name C-C motif chemokine receptor 6
Synonyms gene STRL22
Synonyms gene name chemokine (C-C motif) receptor 6
Synonyms CKR-L3 GPR-CY4 CMKBR6 GPR29 DRY-6 DCR2 BN-1 CD196
Locus 6q27
Discovery year 1997-04-21
GenBank acession U68030
Entrez gene record 1235
Pubmed identfication 8886020
Classification CD molecules C-C motif chemokine receptors
Havana BLAST/BLAT OTTHUMG00000016015

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