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CCT2/TCP1 beta Antibody, Biotin Conjugated

CCT2/TCP1 beta Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, CCT2/TCP1 beta Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCCT2/TCP1 beta
SpecificityThis is a highly specific antibody against CCT2/TCP1 beta
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CCT2/TCP1 beta
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CCT subunit levels also change throughout the cell cycle, CCT2 exhibits both actin and tubulin binding activities (6, CCT2 is the Î, Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2), The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1), This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3), with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4), ², -subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress, 3) but the exact molecular function on this subunit remains uncertain, CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Cctb
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCCT2/TCP1 beta Conjugated
Short name Conjugated, CCT2/TCP1 beta Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CCT2/TCP1 b (Antibody to)
Alternative techniqueantibodies
Identity 1615
Gene CCT2
Long gene name chaperonin containing TCP1 subunit 2
Synonyms gene name chaperonin containing TCP1, subunit 2 (beta)
Locus 12q15
Discovery year 1999-02-26
GenBank acession AF026293
Entrez gene record 10576
Pubmed identfication 9819444
RefSeq identity NM_006431
Classification Chaperonins
Havana BLAST/BLAT OTTHUMG00000169383

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