Name : CD105 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5493761088
| Long name | FITC Conjugated, CD105 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CD105 |
| Specificity | This is a highly specific antibody against CD105 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 510-545/658 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human CD105 |
| Gene ID number | 2022 |
| Swiss Prot | P17813 |
| Tested applications | FCM |
| Recommended dilutions | FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade, Involved in the regulation of angiogenesis, May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors, Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3, Major glycoprotein of vascular endothelium |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | END HHT1 CD105 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD105 Conjugated |
| Short name | FITC Conjugated, CD105 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, CD105 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3349 |
| Gene | ENG |
| Long gene name | endoglin |
| Synonyms gene | ORW1 ORW |
| Synonyms gene name | Osler-Rendu-Weber syndrome 1 |
| Locus | 9q34, 11 |
| Discovery year | 1993-03-03 |
| GenBank acession | AF035753 |
| Entrez gene record | 2022 |
| Pubmed identfication | 8404038 10548503 |
| Classification | CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000020723 |
| Locus Specific Databases | Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database LRG_589 |