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CD11b Antibody

CD11b Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCD11b
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, WB, IHC
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis CD11b antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P11215
PurityAntigen affinity
Description Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), and also in the phagocytosis of complement coated particles, or inactivated-C3b (iC3b) receptor 3 ('CR3'), CD11b is the integrin alpha M chain
ImmunogenA portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD11b antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCD11b
Short nameCD11b Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD11b (Antibody to)
Alternative techniqueantibodies
Identity 1626
Gene CD11B
Long gene name integrin subunit alpha M
Synonyms gene CR3A
Synonyms gene name alpha, alpha M (complement component 3 receptor 3 subunit) , alpha M (complement component receptor 3, also known as CD11b (p170), integrin, macrophage antigen alpha polypeptide) integrin
Synonyms MAC-1 CD11b ITGAM
Synonyms name complement component 3 receptor 3 subunit
Locus 16p11, 2
Discovery year 1988-08-05
GenBank acession J03925
Entrez gene record 3684
RefSeq identity NM_000632
Classification Complement system Integrin alpha subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000176612

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