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CD146 Antibody

CD146 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCD146 Primary Polyclonal Antibody
Also known asCD146 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCD146/MCAM
SpecificityThis is a highly specific antibody against CD146/MCAM
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range200-250/646
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD146
Gene ID number4162
Swiss ProtP43121
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, Could be an adhesion molecule active in neural crest cells during embryonic development, Its expression may allow melanoma cells to interact with cellular elements of the vascular system, and a transient increase in the intracellular calcium concentration, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue, thereby enhancing hematogeneous tumor spread, Plays a role in cell adhesion
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, CD146
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCD146
Short nameCD146 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD146 (Antibody to)
Alternative techniqueantibodies
Identity 6934
Gene MCAM
Long gene name melanoma cell adhesion molecule
Synonyms MUC18 CD146
Synonyms name Gicerin
Locus 11q23, 3
Discovery year 1995-12-18
GenBank acession X68264
Entrez gene record 4162
Pubmed identfication 2602381 10702685
Classification C2-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000166197

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