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CD161 Antibody

CD161 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCD161 Primary Polyclonal Antibody
Also known asCD161 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCD161
SpecificityThis is a highly specific antibody against CD161
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range175-225/225
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD161/NK11
Gene ID number3820
Swiss ProtQ12918
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3, Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide, Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1, Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells, 3)Gal epitope as well as to the N-acetyllactosamine epitope, Plays an inhibitory role on natural killer (NK) cells cytotoxicity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-type lectin domain family 5 member B, CD161, CLEC5B, KLRB1, Killer cell lectin-like receptor subfamily B member 1, NKR-P1, NKR-P1A, NKRP1A, Natural killer cell surface protein P1A, hNKR-P1A, NKR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCD161
Short nameCD161 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD161 (Antibody to)
Alternative techniqueantibodies
Identity 6373
Gene KLRB1
Long gene name killer cell lectin like receptor B1
Synonyms gene NKR
Synonyms gene name killer cell lectin-like receptor subfamily B, member 1
Synonyms CD161 NKR-P1 NKR-P1A hNKR-P1A CLEC5B
Synonyms name natural killer cell surface protein P1A
Locus 12p13, 31
Discovery year 1998-01-16
GenBank acession U11276
Entrez gene record 3820
Pubmed identfication 8077657
RefSeq identity NM_002258
Classification Killer cell lectin like receptors CD molecules C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000168581

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