Name : CD161 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2612812230
| Long name | ALEXA FLUOR 647 Conjugated, CD161 Polyclonal Antibody |
| Also known as | Anti-CD161 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CD161 |
| Specificity | This is a highly specific antibody against CD161 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 175-225/225 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD161/NK11 |
| Gene ID Number | 3820 |
| Swiss Prot | Q12918 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3, Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide, Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1, Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells, 3)Gal epitope as well as to the N-acetyllactosamine epitope, Plays an inhibitory role on natural killer (NK) cells cytotoxicity |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | CD161 NKR-P1 NKR-P1A hNKR-P1A CLEC5B |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CD161 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | CD161 |
| Short name | CD161 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, CD161 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6373 |
| Gene | KLRB1 |
| Long gene name | killer cell lectin like receptor B1 |
| Synonyms gene | NKR |
| Synonyms gene name | killer cell lectin-like receptor subfamily B, member 1 |
| Synonyms name | natural killer cell surface protein P1A |
| Locus | 12p13, 31 |
| Discovery year | 1998-01-16 |
| GenBank acession | U11276 |
| Entrez gene record | 3820 |
| Pubmed identfication | 8077657 |
| RefSeq identity | NM_002258 |
| Classification | Killer cell lectin like receptors CD molecules C-type lectin domain family |
| Havana BLAST/BLAT | OTTHUMG00000168581 |