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CD161 Antibody, Biotin Conjugated

CD161 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CD161 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD161
SpecificityThis is a highly specific antibody against CD161
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range175-225/225
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human CD161/NK11
Gene ID number3820
Swiss ProtQ12918
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3, Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide, Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1, Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells, 3)Gal epitope as well as to the N-acetyllactosamine epitope, Plays an inhibitory role on natural killer (NK) cells cytotoxicity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CD161 NKR-P1 NKR-P1A hNKR-P1A CLEC5B
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD161 Conjugated
Short name Conjugated, CD161 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CD161 (Antibody to)
Alternative techniqueantibodies
Identity 6373
Gene KLRB1
Long gene name killer cell lectin like receptor B1
Synonyms gene NKR
Synonyms gene name killer cell lectin-like receptor subfamily B, member 1
Synonyms name natural killer cell surface protein P1A
Locus 12p13, 31
Discovery year 1998-01-16
GenBank acession U11276
Entrez gene record 3820
Pubmed identfication 8077657
RefSeq identity NM_002258
Classification Killer cell lectin like receptors CD molecules C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000168581

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