Name : CD18 (Ser756 + Thr758 + Thr759) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN1741918631
| Long name | CD18 (Ser756 + Thr758 + Thr759) Antibody |
| Also known as | CD18 (Ser756 + Thr758 + Thr759) Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD18 Ser756 + Thr758 + Thr759 |
| Specificity | This is a highly specific antibody against CD18 Ser756 + Thr758 + Thr759 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser756 + Thr758 + Thr759 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 724-769/769 |
| Subcellular location | Cytoplasm |
| Source | Thr758/759, KLH conjugated synthetic phosphopeptide derived from human CD18 around the phosphorylation site of Ser756 |
| Gene ID number | 3689 |
| Swiss Prot | P05107 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ICAM2, ICAM3 and ICAM4, Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1, Integrin alpha-M/beta-2 is also a receptor for factor X, Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain, Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen, Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation, Integrin alpha-L/beta-2 is a receptor for ICAM1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD18, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, ITGB2, Integrin beta-2, LCAMB, LFA-1, MAC-1, MF17, MFI7, 95 subunit beta, LAD |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD18 (Ser756 + Thr758 + Thr759) |
| Short name | CD18 (Ser756 + Thr758 + Thr759) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD18 (Ser756 and Thr758 and Thr759) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6155 |
| Gene | ITGB2 |
| Long gene name | integrin subunit beta 2 |
| Synonyms gene | CD18 MFI7 |
| Synonyms gene name | beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin |
| Synonyms | LFA-1 MAC-1 |
| Synonyms name | complement component 3 receptor 3 and 4 subunit |
| Locus | 21q22, 3 |
| Discovery year | 1986-01-01 |
| GenBank acession | AK222505 |
| Entrez gene record | 3689 |
| RefSeq identity | NM_000211 |
| Classification | Complement system Integrin beta subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000090257 |
| Locus Specific Databases | ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76 |