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CD272 Antibody

CD272 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCD272 Primary Polyclonal Antibody
Also known asCD272 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCD272
SpecificityThis is a highly specific antibody against CD272
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range239-289/289
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator
Gene ID number151888
Swiss ProtQ7Z6A9
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen B7x, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1), BTLA is not expressed by naive T cells, BTLA-deficient T cells show increased proliferation, Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, Thus, a peripheral homolog of B7, an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis, and attenuates production of interleukin 2 (IL-2), but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells, is a ligand of BTLA, B and T lymphocyte attenuator (BTLA)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA, CD272, BTLA1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCD272
Short nameCD272 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD272 (Antibody to)
Alternative techniqueantibodies
Identity 21087
Gene BTLA
Long gene name B and T lymphocyte associated
Synonyms BTLA1 CD272
Locus 3q13, 2
Discovery year 2003-08-20
GenBank acession AY293286
Entrez gene record 151888
Pubmed identfication 12796776
RefSeq identity NM_181780
Classification Immunoglobulin like domain containing CD molecules
Havana BLAST/BLAT OTTHUMG00000159255

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