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CD272 Antibody, ALEXA FLUOR 488

CD272 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, CD272 Polyclonal Antibody
Also known asAnti-CD272 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD272
SpecificityThis is a highly specific antibody against CD272
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range239-289/289
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator
Gene ID Number151888
Swiss ProtQ7Z6A9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen B7x, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1), BTLA is not expressed by naive T cells, BTLA-deficient T cells show increased proliferation, Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, Thus, a peripheral homolog of B7, an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis, and attenuates production of interleukin 2 (IL-2), but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells, is a ligand of BTLA, B and T lymphocyte attenuator (BTLA)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms BTLA1 CD272
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CD272 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetCD272
Short nameCD272 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, CD272 (Antibody to)
Alternative techniqueantibodies
Identity 21087
Gene BTLA
Long gene name B and T lymphocyte associated
Locus 3q13, 2
Discovery year 2003-08-20
GenBank acession AY293286
Entrez gene record 151888
Pubmed identfication 12796776
RefSeq identity NM_181780
Classification Immunoglobulin like domain containing CD molecules
Havana BLAST/BLAT OTTHUMG00000159255

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