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CD272 Antibody, Cy3 Conjugated

CD272 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, CD272 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD272
SpecificityThis is a highly specific antibody against CD272
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range239-289/289
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator
Gene ID number151888
Swiss ProtQ7Z6A9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background B7x, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1), BTLA is not expressed by naive T cells, BTLA-deficient T cells show increased proliferation, Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, Thus, a peripheral homolog of B7, an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis, and attenuates production of interleukin 2 (IL-2), but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells, is a ligand of BTLA, B and T lymphocyte attenuator (BTLA)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms BTLA1 CD272
Properties 1 of the CD272 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD272 Conjugated
Short name Conjugated, CD272 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, CD272 (Antibody to)
Alternative techniqueantibodies
Identity 21087
Gene BTLA
Long gene name B and T lymphocyte associated
Locus 3q13, 2
Discovery year 2003-08-20
GenBank acession AY293286
Entrez gene record 151888
Pubmed identfication 12796776
RefSeq identity NM_181780
Classification Immunoglobulin like domain containing CD molecules
Havana BLAST/BLAT OTTHUMG00000159255

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