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CD272 Antibody, Cy5 Conjugated

CD272 Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, CD272 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD272
SpecificityThis is a highly specific antibody against CD272
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range239-289/289
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator
Gene ID number151888
Swiss ProtQ7Z6A9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background B7x, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1), BTLA is not expressed by naive T cells, BTLA-deficient T cells show increased proliferation, Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, Thus, a peripheral homolog of B7, an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis, and attenuates production of interleukin 2 (IL-2), but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells, is a ligand of BTLA, B and T lymphocyte attenuator (BTLA)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms BTLA1 CD272
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD272 Conjugated
Short name Conjugated, CD272 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, CD272 (Antibody to)
Alternative techniqueantibodies
Identity 21087
Gene BTLA
Long gene name B and T lymphocyte associated
Locus 3q13, 2
Discovery year 2003-08-20
GenBank acession AY293286
Entrez gene record 151888
Pubmed identfication 12796776
RefSeq identity NM_181780
Classification Immunoglobulin like domain containing CD molecules
Havana BLAST/BLAT OTTHUMG00000159255

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