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CD31 Antibody

CD31 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCD31 Primary Polyclonal Antibody
Also known asCD31 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCD31
SpecificityThis is a highly specific antibody against CD31
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range718-738/738
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD31
Gene ID number5175
Swiss ProtP16284
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rabbit, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions, During apoptosis, Isoform Delta15 is unable to protect against apoptosis, Modulates BDKRB2 activation, Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC), The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore, thus triggering the process of engulfment), Induces susceptibility to atherosclerosis (By similarity)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD31/EndoCAM, GPIIA', PECA1, PECAM-1, PECAM1, Platelet endothelial cell adhesion molecule, endoCAM, CD31
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCD31
Short nameCD31 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD31 (Antibody to)
Alternative techniqueantibodies
Identity 8823
Gene PECAM1
Long gene name platelet and endothelial cell adhesion molecule 1
Synonyms gene name platelet/endothelial cell adhesion molecule 1
Synonyms CD31
Synonyms name CD31 antigen
Locus 17q23, 3
Discovery year 1995-11-29
GenBank acession L34631 M37780
Entrez gene record 5175
Pubmed identfication 8661055 1690453
RefSeq identity NM_000442
Classification CD molecules Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000175829

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