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CD31 Antibody, ALEXA FLUOR 488

CD31 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, CD31 Polyclonal Antibody
Also known asAnti-CD31 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD31
SpecificityThis is a highly specific antibody against CD31
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range621-650/738
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from mouse CD31
Gene ID Number5175
Swiss ProtP16284
Tested applications IF(ICC), IF(IHC-P), FCM
Recommended dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Dog, Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions, During apoptosis, Isoform Delta15 is unable to protect against apoptosis, Modulates BDKRB2 activation, Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC), The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore, thus triggering the process of engulfment), Induces susceptibility to atherosclerosis (By similarity)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms CD31
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CD31 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetCD31
Short nameCD31 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, CD31 (Antibody to)
Alternative techniqueantibodies
Identity 8823
Gene PECAM1
Long gene name platelet and endothelial cell adhesion molecule 1
Synonyms gene name platelet/endothelial cell adhesion molecule 1
Synonyms name CD31 antigen
Locus 17q23, 3
Discovery year 1995-11-29
GenBank acession L34631 M37780
Entrez gene record 5175
Pubmed identfication 8661055 1690453
RefSeq identity NM_000442
Classification CD molecules Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000175829

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