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CD317 Antibody, ALEXA FLUOR 594

CD317 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, CD317 Polyclonal Antibody
Also known asAnti-BST2/CD317 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBST2/CD317
SpecificityThis is a highly specific antibody against BST2/CD317
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-20/180
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BST2
Gene ID Number684
Swiss ProtQ10589
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a direct physical tether, Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration, Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection, In either case, Isoform 1 acts as an activator of NF-kappa-B and this activity is inhibited by isoform 2, Isoform 1 and isoform 2 are both effective viral restriction factors but have differing antiviral and signaling activities, Isoform 2 is resistant to HIV-1 Vpu-mediated degradation and restricts HIV-1 viral budding in the presence of Vpu, Its target viruses belong to diverse families, Mason-Pfizer monkey virus (MPMV), Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells, Rous sarcoma virus (RSV) and murine leukemia virus (MLV), The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface, and paramyxoviridae: nipah virus, arenaviridae: lassa virus (LASV) and machupo virus (MACV), equine infectious anemia virus (EIAV), feline immunodeficiency virus (FIV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), flavivirideae: hepatitis C virus (HCV), herpesviridae: kaposis sarcoma-associated herpesvirus (KSHV), holding virions to the cell membrane and linking virions to each other, human T-cell leukemia virus type 1 (HTLV-1), human immunodeficiency virus type 2 (HIV-2), including retroviridae: human immunodeficiency virus type 1 (HIV-1), orthomyxoviridae: influenza A virus, prototype foamy virus (PFV), rhabdoviridae: vesicular stomatitis virus (VSV), simian immunodeficiency viruses (SIVs), their spread as cell-free virions is restricted, IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CD317 tetherin
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetCD317
Short nameCD317 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, CD317 (Antibody to)
Alternative techniqueantibodies
Identity 1119
Gene BST2
Long gene name bone marrow stromal cell antigen 2
Locus 19p13, 11
Discovery year 1994-11-17
Entrez gene record 684
Pubmed identfication 7607676
RefSeq identity NM_004335
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000191770

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