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CD317 Antibody, Biotin Conjugated

CD317 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CD317 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBST2/CD317
SpecificityThis is a highly specific antibody against BST2/CD317
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1-20/180
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human BST2
Gene ID number684
Swiss ProtQ10589
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a direct physical tether, Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration, Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection, In either case, Isoform 1 acts as an activator of NF-kappa-B and this activity is inhibited by isoform 2, Isoform 1 and isoform 2 are both effective viral restriction factors but have differing antiviral and signaling activities, Isoform 2 is resistant to HIV-1 Vpu-mediated degradation and restricts HIV-1 viral budding in the presence of Vpu, Its target viruses belong to diverse families, Mason-Pfizer monkey virus (MPMV), Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells, Rous sarcoma virus (RSV) and murine leukemia virus (MLV), The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface, and paramyxoviridae: nipah virus, arenaviridae: lassa virus (LASV) and machupo virus (MACV), equine infectious anemia virus (EIAV), feline immunodeficiency virus (FIV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), flavivirideae: hepatitis C virus (HCV), herpesviridae: kaposis sarcoma-associated herpesvirus (KSHV), holding virions to the cell membrane and linking virions to each other, human T-cell leukemia virus type 1 (HTLV-1), human immunodeficiency virus type 2 (HIV-2), including retroviridae: human immunodeficiency virus type 1 (HIV-1), orthomyxoviridae: influenza A virus, prototype foamy virus (PFV), rhabdoviridae: vesicular stomatitis virus (VSV), simian immunodeficiency viruses (SIVs), their spread as cell-free virions is restricted, IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CD317 tetherin
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD317 Conjugated
Short name Conjugated, CD317 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CD317 (Antibody to)
Alternative techniqueantibodies
Identity 1119
Gene BST2
Long gene name bone marrow stromal cell antigen 2
Locus 19p13, 11
Discovery year 1994-11-17
Entrez gene record 684
Pubmed identfication 7607676
RefSeq identity NM_004335
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000191770

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