Name : CD40 (647CT13.2.4) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN7549966995
| Long name | 2, 4) Monoclonal Antibody, CD40 (647CT13 |
| Also known as | 2, 4) Monoclonal Antibody, CD40 (647CT13 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD40 |
| Specificity | This is a highly specific antibody against CD40 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 2, 4, 647CT13 |
| Source | This CD40 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human CD40 |
| Gene ID number | 958 |
| Swiss Prot | P25942 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~1600) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion, Receptor for TNFSF5/CD40LG |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDW40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, p50 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 2, 4) Monoclonal, CD40 (647CT13 |
| Short name | 2, 4) Monoclonal Antibody, CD40 (647CT13 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | tumor necrosis factor receptor superfamily member 5 (647CT13, 2, 4) monoclonal (Antibody to), CD40 molecule |
| Alternative technique | antibodies |
| Alternative to gene target | BT, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, Extracellular, TNF receptor superfamily member 5, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002768 and immune response-regulating cell surface receptor signaling pathway and biological process this GO :0003823 and antigen binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0042100 and B cell proliferation and biological process this GO :0042113 and B cell activation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003823: antigen binding, this GO :0003823: antigen binding and also this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0019899: enzyme binding and also this GO :0031625: ubiquitin protein ligase binding, this GO :0004871: signal transducer activity, this GO :0004872: receptor activity, this GO :0005515: protein binding, this GO :0019899: enzyme binding, this GO :0031625: ubiquitin protein ligase binding, ubiquitin protein ligase binding, 42498 and IDBG-643036 and ENSBTAG00000020736 and 286849, CD40 molecule |
| Identity | 11919 |
| Gene | CD40 |
| Long gene name | CD40 molecule |
| Synonyms gene | TNFRSF5 |
| Synonyms gene name | TNF receptor superfamily member 5 , member 5 CD40 molecule, tumor necrosis factor receptor superfamily |
| Synonyms | p50 Bp50 |
| Locus | 20q13, 12 |
| Discovery year | 1993-08-27 |
| GenBank acession | X60592 |
| Entrez gene record | 958 |
| Pubmed identfication | 7687385 2998589 |
| RefSeq identity | NM_001250 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000033053 |
| Locus Specific Databases | CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base) LRG_40 |