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CD40 Antibody

CD40 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCD40
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the CD40 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis CD40 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P25942
PurityAntigen affinity
Description AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction, The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, and germinal center formation, and thus is thought to be an early event in Alzheimer disease pathogenesis, memory B cell development, which may be important for homotypic cell interactions, The protein encoded by this gene is a member of the TNF-receptor superfamily
ImmunogenA portion of amino acids 247-276 from the human protein was used as the immunogen for this CD40 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD40 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCD40
Short nameCD40 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name tumor necrosis factor receptor superfamily member 5 (Antibody to), CD40 molecule
Alternative techniqueantibodies
Alternative to gene target BT, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, Extracellular, TNF receptor superfamily member 5, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002768 and immune response-regulating cell surface receptor signaling pathway and biological process this GO :0003823 and antigen binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0042100 and B cell proliferation and biological process this GO :0042113 and B cell activation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003823: antigen binding, this GO :0003823: antigen binding and also this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0019899: enzyme binding and also this GO :0031625: ubiquitin protein ligase binding, this GO :0004871: signal transducer activity, this GO :0004872: receptor activity, this GO :0005515: protein binding, this GO :0019899: enzyme binding, this GO :0031625: ubiquitin protein ligase binding, ubiquitin protein ligase binding, 42498 and IDBG-643036 and ENSBTAG00000020736 and 286849, CD40 molecule
Identity 11919
Gene CD40
Long gene name CD40 molecule
Synonyms gene TNFRSF5
Synonyms gene name TNF receptor superfamily member 5 , member 5 CD40 molecule, tumor necrosis factor receptor superfamily
Synonyms p50 Bp50
Locus 20q13, 12
Discovery year 1993-08-27
GenBank acession X60592
Entrez gene record 958
Pubmed identfication 7687385 2998589
RefSeq identity NM_001250
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000033053
Locus Specific Databases CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base) LRG_40

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