| Long name | CD45 Primary Polyclonal Antibody |
| Also known as | CD45 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD45 |
| Specificity | This is a highly specific antibody against CD45 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1210-1260/1304 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD45 |
| Gene ID number | 5788 |
| Swiss Prot | P08575 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as a positive regulator of T-cell coactivation upon binding to DPP4, Dephosphorylates LYN, The first PTPase domain has enzymatic activity, Upon T-cell activation, and thereby modulates LYN activity (By similarity), recruits and dephosphorylates SKAP1 and FYN, while the second one seems to affect the substrate specificity of the first one, Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | B22, CD45, CD45R, GP18, L-CA, LY5, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T2, LCA |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD45 |
| Short name | CD45 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD45 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9666 |
| Gene | PTPRC |
| Long gene name | protein tyrosine phosphatase, receptor type C |
| Synonyms gene | CD45 |
| Synonyms | LCA T200 GP180 |
| Locus | 1q31, 1 , 3-q32 |
| Discovery year | 1986-01-01 |
| GenBank acession | Y00062 |
| Entrez gene record | 5788 |
| Pubmed identfication | 2169617 |
| RefSeq identity | NM_002838 |
| Classification | Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT | OTTHUMG00000035702 |
| Locus Specific Databases | PTPRCbase: Mutation registry for CD45 deficiency LRG_95 |