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CD45/ LCA Antibody

CD45/ LCA Antibody size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD45
Other names C, CD45 antigen, CD_antigen: CD45, L-CA, Leukocyte common antigen, Receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen, c polypeptide, protein tyrosine phosphatase, protein tyrosine phosphatase, receptor type, receptor type, receptor-type tyrosine-protein phosphatase C, receptor-type tyrosine-protein phosphatase C isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene namePTPRC
Gene name synonimsN/A
Other gene names B220, CD45, CD45, CD45R, GP180, L-CA, L-CA, LCA, LY5, PTPRC, T200, PTPRC
ClonalityMonoclonal
Immunoglobulin isotype kappa, kappa + IgG1, IgG1
Clone2B11 + PD7/26
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, 190, 205, A positive result with this MAb is highly indicative of lymphoid or myeloid origin, Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms, Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals, This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors, This particular antibody might cross react with speacies outside of the listed ones, and some leukemias) so its absence does not rule out a hematolymphoid tumor, normal and malignant non-hematopoietic tissues, some T-cell lymphomas, Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD45/ LCA
Short nameCD45/ LCA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD45/ LCA (Antibody to)
Alternative techniqueantibodies
Identity 9666
Gene PTPRC
Long gene name protein tyrosine phosphatase, receptor type C
Synonyms gene CD45
Synonyms LCA T200 GP180
Locus 1q31, 1 , 3-q32
Discovery year 1986-01-01
GenBank acession Y00062
Entrez gene record 5788
Pubmed identfication 2169617
RefSeq identity NM_002838
Classification Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000035702
Locus Specific Databases PTPRCbase: Mutation registry for CD45 deficiency LRG_95

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